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Absolutely.
Supplementary information is an easy option but also the least effective and user-friendly. From day one PLoS ONE can allow as many SI files as anyone could want just so long as no individual file is larger than 10MB--that is no more than we have available on all PLoS journals--but we want to be able to do better than that.
This is of course one of the reasons why the TOPAZ publishing platform is being developed as an Open Source project. We want to enable the people who best understand specific publishing problems to create solutions that can be easily shared.
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