Hi Jason,

I've got to admit I was wondering the same thing, particularly given the broad nature of PLoS ONE -- everything from nuclear physics to cell biology under the same roof is going to (potentially) have a hard time getting the critical mass of people from all disciplines needed for good over-publication peer review and discussion. With PLoS having focused on biological and medical science so far, I suspect that these areas will have a reasonable representation in the beginning, but I'm not sure how easy or hard it will be to grow in, say, physics (my own background).

One thing that I haven't noticed anywhere is the requirements for signing up and commenting on PLoS ONE. Are you going to have to prove in some fashion that you're a scientist? Given the open access theme, one would think everyone should be able to comment on papers, but is this going to lead to a deluge of bad posts (as can be found on a few of the blogs already out there dealing with things like evolution)?

Either way, I also think PLoS ONE is a fantastic idea, and can't wait to see it in action.